Canine Gene Associated with Small Body Size mutated 53,000 ya

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Canine Gene Associated with Small Body Size mutated 53,000 ya

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Researchers have assembled a catalog of 1,431 genomes, inclusive of ancient canines, modern breed dogs, and wild canids, in a search for genetic variants passed from ancient to modern dogs. They’ve identified an ancient mutation in a growth hormone-regulating gene, which has been under human selection, that contributes to a significant portion of body size in modern dogs.
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Scientists have theorized that dogs started out large and became smaller about 20,000 years ago, when they were domesticated, but this discovery presents the possibility of a new evolutionary narrative. Indeed, when Dr. Plassais, Dr. Ostrander and their co-authors looked at the DNA of a 54,000-year-old steppe wolf (Canis lupus campestris) they found that it, too, possessed the growth hormone mutation. “It’s as though Nature had kept it tucked in her back pocket for tens of thousands of years until it was needed,” Dr. Ostrander said.

The finding holds not just for dogs and wolves, but also for coyotes, jackals, African hunting dogs, and other members of the family of animals referred to as canids. “This is tying together so much about canine domestication and body size, and the things that we think are very modern are actually very ancient,” Dr. Ostrander said.
http://www.sci-news.com/paleontology/ca ... 10500.html
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